BDBM200451 US10011599, Example 80::US9227969, 80::US9629836, 80
SMILES CC1(CCN(CC1)C(N)=O)n1cnc2cnc3cc(F)c(cc3c12)-c1ccc(Oc2ncccn2)cc1F
InChI Key InChIKey=FQTDEACKAXRSFD-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 200451
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 13nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair